A Century of DNA: A History of the Discovery of the Structure and Function of the Genetic Substance

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Author: Franklin H. Portugal

ISBN-10: 0262660466

ISBN-13: 9780262660464

Category: Biologists - Biography

Why did it take more than a century of research before scientists properly understood what DNA was and what it did within the cell? A Century of DNA aims to answer this question, tracing the history of DNA research across interrelated subjects, including embryology, biophysics, organic chemistry, histology, physiological chemistry, and genetics. The chapters follow a chronological sequence in the development of ideas on DNA, and incorporate biographical material on researchers involved in...

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The story of DNA from the time of its discovery in 1869 up to the solution of the genetic code in the 1960s.

Foreword p.viiAlexander R. (Lord) ToddPreface p.ixAcknowledgments p.xii1. The Discovery of DNA p.32. The Role of the Nucleus p.313. The Discovery of Nucleic Acid Components p.514. The Tetranucleotide Hypothesis p.715. Early Theories of Heredity p.906. The Evolution of Modern Genetics p.1097. Genetic Transformation by DNA p.1378. The Mechanism of Gene Expression p.1599. The Search for the Chemical Structure of DNA p.18610. The Development of Structural Molecular Biology p.20411. The Three-Dimensional Structure of DNA p.23012. The Genetic Code p.27213. Conclusion and Prologue to the Second Century p.304Notes and References p.322Index p.375

\ From the Publisher"...a considerable contribution to the history of the subject." Nature\ "A major work in the history of science." The Wall Street Journal\ "As detailed and accurate a factual reconstruction as we are likely to be given for a generation" Human Nature\ "The general objective of this book...is laudable." Science\ \ \