Children with Starving Brains: A Medical Treatment Guide for Autism Spectrum Disorder
Children with Starving Brains is a message of hope in the midst of a worldwide epidemic of autism, ADD and ADHD. This is the first book written by an experienced clinician that gives a step-by-step treatment guide for parents and doctors based on the understanding that ASD is a complex biomedical illness resulting in significant brain malnutrition. Genetic susceptibility activated by "triggers" such as pesticides and heavy metals in vaccines can lead to immune system impairment, gut...
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In the midst of a worldwide epidemic of autism, ADD and ADHD, this book is a message of hope to parents embarking on the challenging journey of finding proper medical care for their Autism Spectrum Disorder children. This is the first book written by an experienced clinician that gives a step-by-step treatment guide for parents and doctors based on the understanding that ASD is a complex biomedical illness resulting in significant brain malnutrition. Genetic susceptibility activated by triggers such as pesticides and heavy metals in vaccines can lead to immune system impairment, gut dysfunction, and pathogen invasion such as yeast and viruses in many children. Dr. McCandless, whose grandchild with autism has inspired her broad spectrum approach, describes important diagnostic tools needed to select appropriate treatment programs. Her book explains major therapies newly available and identifies safe and effective options for parents and physicians working together to improve the health of these special children.
About the Author xiiDedication xiiiPreface to 1st & 2nd Editions and Acknowledgements xivPreface to 3rd Edition (Book Description) xixIntroductionChildren With Real Medical Illnesses 1A Message of Hope 1Defeat Autism Now! 3What Can a Parent Expect From Biomedical Interventions? 6My Personal and Professional Involvement in the Bio-Medicine of Autism 8My Most Challenging Case 101 Causation Models 15The Worldwide Autism Spectrum Disorder (ASD) Epidemic 15Definition of ASD and Incidence of Classic vs. Regressive Autism 16What Causes Autism and Other ASDs? 17Simply Genetic? 18The Toxic Chemical Model 19The Heavy Metal Contamination Model 20Vaccinations 21The Auto-immunity/Allergy Model 24The Viral Model 26The Gluten/Casein, Enzyme Deficiency and Yeast Overgrowth Model 27The Metallothionein Theory 29How Models of Causation Lead to Treatments That Work 302 Gastrointestinal Pathology-Nutritional Deficiencies 35Nutritional Deficiency as a Common Denominator 35Causes of Gastrointestinal Problems in ASD Children 38How the Immune and GI Systems Interact 39How Yeast Overgrowth Can Injure the Gastrointestinal System 41"Leaky Gut", Increased Permeability of the Intestinal Mucosa and Malabsorption 42Further Notes on the Mercury/Vaccine Connection 44Putting the Puzzle Pieces Together 443 Impaired Detoxification, Toxic Accumulations, and Politics 48Toxic Threats to Child Development 48The Mechanism of Heavy Metal Toxicity 51Specific Heavy Metals: Lead and Mercury 52Lead 52Mercury 53Mercury in Vaccines 54The Saga of Several Autism Parents and "Parent Power" 564 Clinical and DiagnosticEvaluation 60Biomedical Evaluation 60Family and Medical History 61Pre-testing Considerations 63New Diagnostics in ASD Based on Screening 64Initial Strategies in Test Evaluation 65More Tests, New Philosophy 65Parents, Doctors, and Testing Philosophy 66Descriptions of Specific Laboratory Tests 69Necessary Preliminary Screening Tests 69Complete Blood Count (CBC) with Differential and Platelets 69Comprehensive Metabolic Panel 69Thyroid Panel 69Urinalysis 69Hair Analysis (Part of Heavy Metal Screening) 69Specialized Laboratory Tests as Individually Indicated 71Urinary Peptide Tests for Casein and Gluten 72Organic Acid Test (OAT-urine) 7390-Food IgG Antibodies Test (Serum) 73Amino Acids (Plasma) 74Comprehensive Microbial Digestive Stool Analysis 75Fatty Acid Analysis (Plasma) 75Tests for Metallothionein Dysfunction 76Laboratory Testing in Chelation Therapy 76Immunology Testing 77Which Laboratories to Use 775 Gastrointestinal Healing 80Gastrointestinal Health is a Key Issue 80Treatments That Can Be Implemented by Parents 83The GF/CF/SF (Gluten, Casein, Soy Free) Diet 83How to Start the Diet 85Where to Get Help 86Enzymes 90Probiotics 92Basic Nutrient Supplementation 93Gastrointestinal Treatments That Require Physician Participation 95Anti-fungal Treatment 96Other Gut Pathogens and Treatments 99The Secretin Story 100Summary-Gut Health and Healing 1056 Feeding the Starving Brain 109Vital Nutrients 109Nutritional Deficiencies Identified in Our Children 111The Use of Vital Nutrients 112Primary Recommended Supplements 114The Rationale Behind the Use of Specific Nutrients 119B6 and Magnesium 119Zinc 120Calcium 121Selenium 121Vitamin A and High-Dose Vitamin A Protocol 121Vitamins C and E 122Essential Fatty Acids 123DMG and TMG 124B-Vitamins 125Amino Acids 127Additional Minerals 127Nutrient Interactions 128Testing for Nutritional Deficiencies 128Parents Say Nutrients Help Their Children 1297 Removing the Heavy Metals 133Heavy Metal Toxicity 133A Practical Approach to the Removal of Mercury 135Pre-Chelation Testing 139Hair Analysis 139Porphyrin Testing 140Pre- and Post-Challenge Urine Toxic Elements Test 141RBC Essential Elements 142Cysteine 142Gut Readiness Before Starting Chelation 142Organic Acid Test (OAT) 143Comprehensive Microbial Digestive Stool Analysis 143Nutrient/Mineralization Readiness 144Heavy Metal Detoxification per 2005 Defeat Autism Now! Consensus, Summary 145Phase I, DMSA (Di-mercaptosuccinic Acid) Dosages and Timing 147Dosages, DMSA 147Lab Monitoring 148Readiness for Second Phase: Adding A-lipoic Acid (ALA) 148Second Phase, Laboratory Monitoring 149Completion of Chelation Process 150Alternative Detoxification Treatment 152Allithiamine: Transdermal Thiamine Tetrahydrofurfuryl Disulfide (TTFD) 152Summary 157General Comments on Detoxification Treatment 1588 Immunity, Autoimmunity and Viruses 164An Overview of Immune Dysregulation in ASD Children 164Genetics 164Immune Abnormalities 165Autoimmunity and Autism 166Pathogens and Autoimmunity 166Gastrointestinal Disease and Autism Spectrum Disorder 167MMR and Developmental Regression 167Fungal Infections and the Immune System 167Atypical Elevations of Common Viral Titers 168Allergy and Immunity 168Chronic Low-grade Infections 169Diagnostics-Immune Testing 169Comprehensive (Herpes) Viral Screen 170Myelin Basic Protein (MBP) Antibodies 170Case History-Suzie 170Anti-Viral and Immune Treatment Issues 173Treatments to Enhance the Immune System 175Immunomodulators and Immune Boosters 175Natural Immunomodulators 176Probiotics as Immunomodulators 178Glutathione, or GSH 179IVIG (Intravenous Immune Globulin [Human]) 180High-Dose Vitamin A Protocol 180Prescription Immune-Enhancing Medications 181Anti-viral Prescription Medications 181A Parent's Story-Stan Kurtz 182Viral/Immune Treatment Summary 1849 Hbot-Hyperbaric Oxygen Therapy for Autism Spectrum Disorders James Neubrander Dan Rossignol 190Foreword 191History and Description 191Benefits 192Side Effects 195Multiple Mechanisms of Action 197Basic Principles and Safe Protocols 198Questions and Concerns 199Summary 203Selected Bibliography 20310 Latest Developments 205A Methylation Richard Deth Jaquelyn McCandless 206B Genetic Testing for Methylation Defects Cynthia Schneider 216C Actos Michael Elice 222D Low-Dose Naltrexone Jaquelyn McCandless 227E Low Oxalate Diet Susan Owens 23611 Mitochondrial Dysfunction & Treatments 247A Introduction 247B Treatment Issues 2521 Drugs and Medical States That Negatively Affect Mitochondria 2522 Testing for Mitochondrial Dysfunction 2533 Current Mainstream Medical Treatment Strategies for Mitochondrial Disorder 2544 Mitochondrially Targeted Nutrients to Treat ASD 255Important Nutrients for Supporting Mitochondrial Health 25712 Starving Brains, Starving Hearts, What Does It All Mean? Jack Zimmerman 268Messages 268Jaquelyn, Chelsey and Elizabeth 271Awareness of Subtle Relationships 282Final Words 284AppendicesAppendix A Progress in Gastrointestinal Research and Its Relationship to Immunity in Autism Teresa Binstock 286Appendix B Autism, Metals, and the Mercury in Vaccines, and the alternative version of the "Autism/Mercury Paper" Sallie Bernard Albert Enayati Heidi Roger Lyn Redwood Teresa Binstock.Introductory Comments Teresa Binstock 293Appendix C Intra-Body Toxins Teresa Binstock 320Appendix D Mitochondrial Concerns Teresa Binstock 330Appendix E Implications for Medicine, Education and the Environment Jack Zimmerman 343A Poetic Version of our Journey with Chelsey 362Index 383
