Molecular Biology of the Cell, 5th Edition
For nearly a quarter century Molecular Biology of the Cell has been the leading cell biology textbook. This tradition continues with the new Fifth Edition, which has been completely revised and updated to describe our current, rapidly advancing understanding of cell biology. To list but a few examples, a large amount of new material is presented on epigenetics; stem cells; RNAi; comparative genomics; the latest cancer therapies; apoptosis (now its own separate chapter); and cell cycle...
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For nearly a quarter century Molecular Biology of the Cell has been the leading cell biology textbook. This tradition continues with the new Fifth Edition, which has been completely revised and updated to describe our current, rapidly advancing understanding of cell biology. To list but a few examples, a large amount of new material is presented on epigenetics; stem cells; RNAi; comparative genomics; the latest cancer therapies; apoptosis (now its own separate chapter); and cell cycle control and the mechanics of M phase (now integrated into one chapter).The hallmark features of Molecular Biology of the Cell have been retained, such as its consistent and comprehensive art program, clear concept headings, and succinct section summaries. Additionally, in response to extensive feedback from readers, the Fifth Edition now includes several new features.It is now more portable. Chapters 1-20 are printed and Chapters 21-25, covering multicellular systems, are provided as PDF files on the free Media DVD-ROM which accompanies the book.* And for the first time, Molecular Biology of the Cell now contains end-of-chapter questions. These problems, written by John Wilson and Tim Hunt, emphasize a quantitative approach and the art of reasoning from experiments, and they will help students review and extend their knowledge derived from reading the textbook. The Media DVD-ROM, which is packaged with every copy of the book, contains PowerPoint® presentations with all of the figures, tables and micrographs from the text (available as JPEGs too). Also included is the Media Player, which plays over 125 movies—animations, videos, and molecular models—all with voice-over narration. A new reader-friendly feature is the integration of media codes throughout the text that link directly to relevant videos and animations. The Media DVD-ROM holds the multicellular systems chapters (21-25) of the text as well.By skillfully extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and thereby create a coherent framework through which readers may approach and enjoy this subject that is so central to all of biology.* There is also a reference edition of Molecular Biology of the Cell, Fifth Edition (ISBN 978-0-8153-4111-6) that contains Chapters 1-25 entirely in printed format. Development (Company of Biologists) It has been 25 years since the first edition of Molecular Biology of the Cell (MBoC) was published, which means that roughly half of today's practicing scientists do not remember life without this cell biology 'bible'. The other half might recall how the book almost instantly filled a void with refreshingly clear and engaging writing illustrated with extensive diagrams and figures . . . .MBoC has only improved over its several editions, growing with the rapid advances in the field to become an essential resource for students at all levels and a trusted first stop for researchers transitioning into unfamiliar areas of cell biology . . . .An enduring strength of the book is that it remains a comprehensive textbook . . . .In addition to the comprehensive updating of every chapter, another reason to consider acquiring edition five is the improved integration of the print volume with an extensive array of videos and animations in the 'Cell Biology Interactive' provided on the accompanying DVD . . . .Another welcome improvement in MBoC5 helps link the textbook to the lab - there are now problems printed at the ends of the first 20 chapters. Whereas some are designed to facilitate information retention, the best problems stimulate thought and challenge the reader to think about experimental approaches for learning new things about cell biology . . . .the MBoC5 package is a fantastic resource and well worth the upgrade.\\
Special FeaturesList of TopicsAcknowledgmentsA Note to the ReaderPt. IIntroduction to the Cell1Cells and Genomes32Cell Chemistry and Biosynthesis473Proteins129Pt. IIBasic Genetic Mechanisms4DNA and Chromosomes1915DNA Replication, Repair, and Recombination2356How Cells Read the Genome: From DNA to Protein2997Control of Gene Expression375Pt. IIIMethods8Manipulating Proteins, DNA, and RNA4699Visualizing Cells547Pt. IVInternal Organization of the Cell10Membrane Structure58311Membrane Transport of Small Molecules and the Electrical Properties of Membranes61512Intracellular Compartments and Protein Sorting65913Intracellular Vesicular Traffic71114Energy Conversion: Mitochondria and Chloroplasts76715Cell Communication83116The Cytoskeleton90717The Cell Cycle and Programmed Cell Death98318The Mechanics of Cell Division1027Pt. VCells in their Social Context19Cell Junctions, Cell Adhesion, and the Extracellular Matrix106520Germ Cells and Fertilization112721Development of Multicellular Organisms115722Histology: The Lives and Deaths of Cells in Tissues125923Cancer131324The Adaptive Immune System136325Pathogens, Infection, and Innate Immunity1423GlossaryIndexTables: The Genetic Code, Amino Acids
