Physical Methods to Characterize Pharmaceutical Proteins

Hardcover
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Author: James N. Herron

ISBN-10: 0306450267

ISBN-13: 9780306450266

Category: Basic Sciences

This collection of state-of-the-art research describes the most frequently used techniques for structural analysis of proteins. Chapters focus on the impressive progress that has been made in the development of these techniques and identify future trends and research needs. Papers feature several spectroscopic techniques-including fluorescence spectroscopy, circular dichroism, and infrared spectroscopy.\ \ \ Fourier transform infrared spectroscopy investigations of...

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This collection of state-of-the-art research describes the most frequently used techniques for structural analysis of proteins. Chapters focus on the impressive progress that has been made in the development of these techniques and identify future trends and research needs. Papers feature several spectroscopic techniques-including fluorescence spectroscopy, circular dichroism, and infrared spectroscopy. Booknews Reports on the current status and research trends of methods to characterize the physical traits of proteins used in vaccines and therapeutic and diagnostic pharmaceuticals. Considers several spectroscopic techniques, chromatography, capillary electrophoresis, and genetic engineering to analyze such features as three-dimensional structure, hydrodynamic and thermodynamic properties, and kinetics, especially of liquid and freeze-dried products during their shelf life. Annotation c. Book News, Inc., Portland, OR (booknews.com)

Ch. 1Application of Fluorescence Spectroscopy for Determining the Structure and Function of ProteinsCh. 2Structural Information on Proteins from Circular Dichroism Spectroscopy: Possibilities and LimitationsCh. 3Fourier Transform Infrared Spectroscopy Investigations of Protein StructureCh. 4Mass Spectrometry in Protein Structural AnalysisCh. 5Two-, Three-, and Four-Dimensional Nuclear Magnetic Resonance Spectroscopy of Protein PharmaceuticalsCh. 6Thermodynamic Strategies for Rational Protein and Drug DesignCh. 7Chromatographic Techniques for the Characterization of ProteinsCh. 8Capillary Electrophoresis of ProteinsCh. 9Applying Genetic Engineering to the Structural Analysis of ProteinsIndex

\ BooknewsReports on the current status and research trends of methods to characterize the physical traits of proteins used in vaccines and therapeutic and diagnostic pharmaceuticals. Considers several spectroscopic techniques, chromatography, capillary electrophoresis, and genetic engineering to analyze such features as three-dimensional structure, hydrodynamic and thermodynamic properties, and kinetics, especially of liquid and freeze-dried products during their shelf life. Annotation c. Book News, Inc., Portland, OR (booknews.com)\ \