Structure-Based Study of Viral Replication (with Cd-Rom)
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This book addresses the innovative themes in characterizing the cellular membrane platforms and intracellular networking, as well as the architectural aspects of cell compartments mediated by the entry and replication cycles of viruses. The instrumentation of modern molecular and cellular biology provides a potent array of wave packets to image, detect and manipulate major dynamics of macromolecular and subviral assemblies as in the host cellular context.The book includes case studies presented with highly coherent and structured illuminations, including microscopy, spectroscopy and scanning probes. The compilation and integration of the methodology provides time-resolved observations on the reactivity of structures from near-atomic resolution to various molecular or cellular levels of descriptors. The book provides a broad introduction to the various fascinating virus systems and may be used as an advanced textbook by graduate students in biomedicine. It provides adequate background material to explore further the research problems of epidemics in the 21st century.
List of Contributors ixHuman Rhinovirus Cell Entry and Uncoating Renate Fuchs Dieter Blaas 1Role of Lipid Microdomains in Influenza Virus Multiplication Makoto Takeda 43Functions of Integrin [alpha]2[beta]1, A Collagen Receptor, in the Internalization of Echovirus 1 Varpu Marjomaki Mikko Huhtala Mikko Karjalainen Timo Hyypia Jyrki Heino 63Entry Mechanism of Murine and SARS Coronaviruses - Similarity and Dissimilarity Fumihiro Taguchi 77Hepatitis Viruses, Signaling Events and Modulation of the Innate Host Response Syed Mohammad Moin Anindita Kar-Roy Shahid Jameel 91Virus-Cell Interaction of HCV Hideki Tani Yasumasa Komoda Chang-kwang Limn Kensuke Suzuki Kohji Moriishi Tatsuo Miyamura Yoshiharu Matsuura 125RNA Replication of Hepatitis C Virus Hideki Aizaki Tetsuro Suzuki 151Structure and Dynamics in Viral RNA Packaging Thorsten Dieckmann Marta Zumwalt 173Rational Design of Viral Protein Structures with Predetermined Immunological Properties James Lara Yury Khudyakov 199Bioinformatics Resources for the Study of Viruses at the Virginia Bioinformatics Institute Anjan Purkayastha Oswald Crasta J. Dana Eckart Michael Czar X. J. Meng Joao Setubal Bruno Sobral 267Virus Architecture Probed by Atomic Force Microscopy A. J. Malkin Yu. G. Kuznetsov M. Plomp A. McPherson 289Filovirus Assembly and Budding Takeshi Noda Yoshihiro Kawaoka 311Challenges in Designing HIV Env Immunogens for Developing a Vaccine Indresh K. Srivastava R. Holland Cheng 327Insights into the Caliciviridae Family Grant Hansman 381Mathematical Approaches for Stoichiometric Quantification in Studies of Viral Assembly and DNA Packaging Peixuan Guo Jeremy Hall Tae Jin Lee 401Virus-like Particles of Fish Nodavirus Chan-Shing Lin 449The Assembly of the Double-Layered Capsids of Phytoreoviruses Toshihiro Omura Naoyuki Miyazaki Hisashi Naitow R. Holland Cheng Tomitake Tsukihara Atsushi Nakagawa 463Structure and Assembly of Human Herpesviruses: New Insights From Cryo-Electron Microscopy and Tomography Z. Hong Zhou Pierrette Lo 483Human Papillomavirus Type 16 Capsid Proteins: Immunogenicity and Possible Use as Prophylactic Vaccine Antigens Tadahito Kanda Kei Kawana Hiroyuki Yoshikawa 517Chimeric Recombinant Hepatitis E Virus-like Particles Presenting Foreign Epitopes as a Novel Vector of Vaccine by Oral Administration Yasuhiro Yasutomi 539Nucleocapsid Protein of Hantaviruses (Bunyaviridae): Structure and Functions Alexander Plyusnin Vibhor Kumar Olli Vapalahti Peter Engelhardt 553Astrovirus Replication: An Overview Susana Guix Albert Bosch Rosa M. Pinto 571DNA Vaccines against Viruses Britta Wahren Margaret Liu 597Life Cycles of Polyomaviridae - DNA Tumor Virus Masaaki Kawano Hiroshi Handa R. Holland Cheng 609Index 631
