Molecules of Life and Mutations: Understanding Diseases by Understanding Proteins
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This book provides insights into the structures and functions of 130 of the most important biomolecules and their interactions with other endogenous or exogenous molecules. These interactions are illustrated by 3-dimensional images of their atomic structures rather than by abstract formulas or acronyms. The author has compiled an extraordinary collection of molecules which he has visualized in pictures of stunning clarity and beauty by applying molecular modelling software to their atomic coordinate files (deposited in the Brookhaven Protein Data Bank (PDB)). Together with short explanatory texts they provide the reader with a deepened understanding of biological phenomena in the normal as well as the diseased organism.
Ligands - Small Molecules1Nonpeptidic 'Small Molecules'1Peptidic and Proteohormones17Peptidic Toxins27Pictorial Representations of ProteinsLigandLigand-Binding ProteinLigand-Binding Proteins - Large Molecules31Enzymes31Membrane Receptors43Signal Transduction Proteins53Multimodular Adhesion Proteins61DNA-Binding Proteins65Immunological Proteins87Miscellaneous Macromolecules97Epilogue105Index107Internet Resources111
