Nanotechnology and Tissue Engineering: The Scaffold
Nanofabrication gives us the ability to mimic biological structures with molecular level precision. Offering a natural progression of topics, Nanotechnology and Tissue Engineering: The Scaffold provides a state-of-the-art account of groundbreaking research in this rapidly emerging area of biomedical engineering.\ Emphasizing the importance of scaffolds, the book details fundamental and advanced aspects of nanofabrication and examines cellular interactions at the nanoscale level. It reviews...
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Nanofabrication gives us the ability to mimic biological structures with molecular level precision. Offering a natural progression of topics, Nanotechnology and Tissue Engineering: The Scaffold provides a state-of-the-art account of groundbreaking research in this rapidly emerging area of biomedical engineering. Emphasizing the importance of scaffolds, the book details fundamental and advanced aspects of nanofabrication and examines cellular interactions at the nanoscale level. It reviews extracellular matrix structure and function and discusses various nanoscale biological surface modifications that can improve cellular responses. The editors present the most promising nanofabrication techniques, including electrospinning, lithography, and self assembly. Featuring the contributions of pioneering scientists writing about their own research, this cutting-edge volume —Provides background information discussing the emerging importance of scaffolds in tissue engineeringExamines tissue engineering as it relates to orthopedic, cardiovascular, neural, and musculoskeletal applicationsDetails cell responses to a number of nanoscale featuresDelves into microfabrication techniques in scaffold developmentPresents research on designer self-assembling peptide scaffolds This highly comprehensive resource also discusses clinical implications and applications, presenting exciting breakthroughs in neural, vascular, and musculoskeletal tissue engineering with nanostructures. An essential resource, for biomedical engineers working on the frontiers of tissue research, this book brings together current findings and background information on a complete range of engineering processes that have led to the development of a number of highly useful tissues.
Sect. I Importance of Scaffolds in Tissue EngineeringCh. 1 Tissue Engineering: The Therapeutic Strategy of the Twenty-First Century Fan Yang Fan, Yang William L. Neeley Neeley, William L. Michael J. Moore Moore, Michael J. Jeffrey M. Karp Karp, Jeffrey M. Anita Shukla Shukla, Anita Robert Langer Langer, Robert 3Ch. 2 Top-Down Analysis of a Dynamic Environment: Extracellular Matrix Structure and Function Mandana Veiseh Veiseh, Mandana Eva A. Turley Turley, Eva A. Mina J. Bissell Bissell, Mina J. 33Ch. 3 Functions and Requirements of Synthetic Scaffolds in Tissue Engineering Tejas Shyam Karande Karande, Tejas Shyam C. Mauli Agrawal Agrawal, C. Mauli 53Ch. 4 Microfabrication Techniques in Scaffold Development Christopher J. Bettinger Bettinger, Christopher J. Jeffrey T. Borenstein Borenstein, Jeffrey T. Robert Langer Langer, Robert 87Sect. II Effect of Nanostructures on Cellular Responses and Tissue RegenerationCh. 5 Cell Response to Nanoscale Features and Its Implications in Tissue Regeneration: An Orthopedic Perspective Batur Ercan Ercan, Batur Thomas Webster Webster, Thomas 123Ch. 6 Surface Modification of Biomaterials at the Nanoscale: Biomimetic Scaffolds for Tissue Engineering Applications Duron A. Lee Lee, Duron A. Cato T. Laurencin Laurencin, Cato T. 163Sect. III Promising Nanofabrication Techniques to Develop Scaffolds for Tissue EngineeringCh. 7 Electrospun Polymeric Nanofiber Scaffolds for Tissue Regeneration Syam Prasad Nukavarapu Nukavarapu, Syam Prasad Sangamesh G. Kumbar Kumbar, Sangamesh G. Jonathan G. Merrell Merrell, Jonathan G. Cato T. Laurencin Laurencin, Cato T. 199Ch. 8 Structure and Mechanical Properties of ElectrospunNanofibers and Nanocomposites Eunice Phay Shing Tan Tan, Eunice Phay Shing Chwee Teck Lim Lim, Chwee Teck 221Ch. 9 Electrospinning Techniques to Control Deposition and Structural Alignment of Nanofibrous Scaffolds for Cellular Orientation and Cytoskeletal Reorganization Joel K. Wise Wise, Joel K. Michael Cho Cho, Michael Eyal Zussman Zussman, Eyal Constantine M. Megaridis Megaridis, Constantine M. Alexander L. Yarin Yarin, Alexander L. 243Ch. 10 Nanolithographic Techniques in Tissue Engineering Benjamin Moody Moody, Benjamin Gregory S. McCarty McCarty, Gregory S. 261Ch. 11 Designer Self-Assembling Peptide Scaffolds for Tissue Engineering and Regenerative Medicine Akihiro Horii Horii, Akihiro Xiumei Wang Wang, Xiumei Shuguang Zhang Zhang, Shuguang 283Sect. IV Applications of Nanostructured Scaffolds in Biology and MedicineCh. 12 Nanotechnologies in Neural Tissue Engineering Vivek Mukhatyar Mukhatyar, Vivek Julie Yeh Yeh, Julie Ravi Bellamkonda Bellamkonda, Ravi 295Ch. 13 Nanotechnologies for Cardiovascular Tissue Engineering Kristen A. Wieghaus Wieghaus, Kristen A. Edward A. Botchwey Botchwey, Edward A. 311Ch. 14 Nanostructures for Musculoskeletal Tissue Engineering Susan Liao Liao, Susan Casey K. Chan Chan, Casey K. Seeram Ramakrishna Ramakrishna, Seeram 329Index 353
