Single-Channel Recording
Edited by the 1991 winners of the Nobel Prize in Physiology or Medicine, this Second Edition includes new chapters covering such applications as capacitance measurements; single-cell PCR measurements; whole-cell recording from brain slices in combination with imaging techniques; atomic force microscopy of cells and membranes attached to glass pipettes; and patch clamping.\ \ \ Guide to data acquisition & analysis/electronic design of the patch clamp/the giant...
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Edited by the 1991 winners of the Nobel Prize in Physiology or Medicine, this Second Edition includes new chapters covering such applications as capacitance measurements; single-cell PCR measurements; whole-cell recording from brain slices in combination with imaging techniques; atomic force microscopy of cells and membranes attached to glass pipettes; and patch clamping. Booknews The single-channel recording technique has reached the status of a routine method, and the view that conductance changes in biological membranes are caused by the openings and closings of ion channels is now almost universally accepted. This volume contains 22 chapters in four parts: introduction to patch clamping; methods; analysis; and "classics." There is also an appendix on improved patch-clamp techniques for high-resolution current recording from cells and cell- free membrane patches. The first edition was published in 1983. Annotation c. Book News, Inc., Portland, OR (booknews.com)
Ch. 1A Practical Guide to Patch ClampingCh. 2Tight-Seal Whole-Cell RecordingCh. 3Guide to Data Acquisition and AnalysisCh. 4Electronic Design of the Patch ClampCh. 5Low-Noise RecordingCh. 6Voltage Offsets in Patch-Clamp ExperimentsCh. 7Techniques for Membrane Capacitance MeasurementsCh. 8Patch-Pipette Recordings from the Soma, Dendrites, and Axon of Neurons in Brain SlicesCh. 9Patch Clamp and Calcium Imaging in Brain SlicesCh. 10Fast Application of Agonists to Isolated Membrane PatchesCh. 11Electrochemical Detection of Secretion from Single CellsCh. 12Technical Approaches to Studying Specific Properties of Ion Channels in PlantsCh. 13The Giant Membrane PatchCh. 14A Fast Pressure-Clamp Technique for Studying Mechanogated ChannelsCh. 15Electrophysiological Recordings from Xenopus OocytesCh. 16Polymerase Chain Reaction Analysis of Ion Channel Expression in Single Neurons of Brain SlicesCh. 17Force Microscopy on Membrane Patches: A PerspectiveCh. 18The Principles of the Stochastic Interpretation of Ion-Channel MechanismsCh. 19Fitting and Statistical Analysis of Single-Channel RecordsCh. 20A Q-Matrix Cookbook: How to Write Only One Program to Calculate the Single-Channel and Macroscopic Predictions for Any Kinetic MechanismCh. 21Geometric Parameters of Pipettes and Membrane PatchesCh. 22Conformational Transitions of Ionic ChannelsAppendix: Improved Patch-Clamp Techniques for High-Resolution Current Recording from Cells and Cell-Free Membrane PatchesIndex
\ BooknewsThe single-channel recording technique has reached the status of a routine method, and the view that conductance changes in biological membranes are caused by the openings and closings of ion channels is now almost universally accepted. This volume contains 22 chapters in four parts: introduction to patch clamping; methods; analysis; and "classics." There is also an appendix on improved patch-clamp techniques for high-resolution current recording from cells and cell- free membrane patches. The first edition was published in 1983. Annotation c. Book News, Inc., Portland, OR (booknews.com)\ \
