Mechanosensitive Ion Channels
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This book explores the latest data dealing with mechanosensitive channels research results. It was compiled by a group of internationally recognized scientists leading in the field of mechanosensitive ion channels or mechanically gated channels and signaling cascades research. Key problems of cell mechanobiology are also discussed. As a whole, the volume dwells on the major issues of mechanical stress influencing the ion channels and intracellular signaling pathways.
Foreword Max J. Lab viiForeword Jurgen Hescheler xiEditorial xiiiContributors xixMechanosensitive ChannelsExperimental Methods of Studying Mechanosensitive Channels and Possible Errors in Data Interpretation Andre Kamkin Irina Kiseleva Ilya Lozinsky 3The Role of Lipid Bilayer Mechanics in Mechanosensation Tristan Ursell Jane Kondev Dan Reeves Paul A. Wiggins Rob Phillips 37Mechanosensitive Channels Gated by Membrane Tension Paul Blount Yuezhou Li Paul C. Moe Irene Iscla 71Computational Studies of the Bacterial Mechanosensitive Channels Ben Corry Boris Martinac 103Mechanosensory Transduction in the Nematode Caenorhabditis elegans Nikos Kourtis Nektarios Tavernarakis 117Mechanosensitive Ion Channels in Odontoblasts Henry Magloire Bruno Allard Marie-Lise Couble Jean-Christophe Maurin Francoise Bleicher 147Potassium Ion Channels in Articular Chondrocytes Ali Mobasheri Caroline Dart Richard Barrett-Jolley 157Osmotransduction Through Volume-Sensitive Cl[superscript -] Channels Naomi Niisato Yoshinori Marunaka 179Mechanosensitive Channel TRPV4 Makoto Suzuki 203Mechanosensitive Signalling CascadesMechanosensitive Purinergic Calcium Signalling in Articular Chondrocytes Belinda Pingguan-Murphy Martin M. Knight 235Signal Transduction Pathways Involved in Mechanostransduction in Osteoblastic and Mesenchymal Stem Cells Astrid Liedert Lutz Claes Anita Ignatius 253Caveolae: Co-ordinating Centres for Mechanotransduction in the Heart? Sarah Calaghan 267Multimodal Activation and Regulation of Neuronal Mechanosensitive Cation Channels Mario Pellegrino Cristina Barsanti Monica Pellegrini 291Regulation of Intracellular Signal Transduction Pathways by Mechanosensitive Ion Channels Aladin M. Boriek Ashok Kumar 303Cell MechanobiologyThe Effects of Mechanical Stimulation on Vertebrate Hearts Holly A. Shiels Ed White 331Mechanobiology of Fibroblasts Bhavani P. Thampatty James H-C. Wang 351Index 379
