Bioseparations Engineering

Hardcover
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Author: Ladisch

ISBN-10: 0471244767

ISBN-13: 9780471244769

Category: Biochemical Engineering

Multidisciplinary resource for graduate studies and the biotechnology industry Knowledge of the genetic basis of biological functioning continues to grow at an astronomical rate, as do the challenges and opportunities of applying this information to the production of therapeutic compounds, specialty biochemicals, functional food ingredients, environmentally friendly biocatalysts, and new bioproducts from renewable resources. While genetic engineering of living organisms transforms the science...

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Predicting a century of biotechnology just beginning, Ladisch (Purdue U.) reviews the techniques that have been developed over the past couple decades to separate biological compounds in the hope that the explanations will apply to bioproducts not yet invented and biological molecules not yet produced on a large scale as well as to those currently being used. When possible, he provides mechanistic analysis of key phenomena at the microscopic scale. Among the topics he discusses are sedimentation, centrifugation, filtration, membrane separations, precipitation, crystallization, extraction, and the principles and scale-up of liquid chromatography. The price of the European original would be $150. Annotation c. Book News, Inc., Portland, OR (booknews.com)

PrefaceAcknowledgements1Bioseparations12Sedimentation, Centrifugation, and Filtration163Membrane Separations524Precipitation, Crystallization, and Extraction1165Principles of Liquid Chromatography1946Liquid Chromatography Scale-Up2997Principles of Gradient Elution Chromatography4498Principles of Bioseparations for Biopharmaceuticals and Recombinant Protein Products5149Affinity Chromatography: Bridge Between Molecular Biology, Combinatorial Methods, and Separations Science621Author Index707Subject Index713

\ From the Publisher"a comprehensive text that has brought together the theory and practice of bioseperations in an intelligent and well-presented fashion." (Bioseperations Engineering (Food & Bioproducts Processing, December 2001)\ "...Ladish reviews the techniques that have been developed over the past couple decades...in the hope that the explanations will apply to bioproducts not yet invented and biological molecules not yet produced...as well as to those currently being used." (SciTech Book News, Vol. 25, No. 4, December 2001)\ \ \